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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP1 All Species: 20.91
Human Site: S239 Identified Species: 30.67
UniProt: P36776 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36776 NP_004784.2 959 106489 S239 K H K P R R K S K R G K K E A
Chimpanzee Pan troglodytes XP_001143873 959 106437 S239 K H K P R R K S K R G K K E A
Rhesus Macaque Macaca mulatta XP_001088663 909 101136 S239 K H K P R R K S K R G K K E A
Dog Lupus familis XP_854391 960 106631 T240 K Q K P R R K T K R G K K E V
Cat Felis silvestris
Mouse Mus musculus Q8CGK3 949 105824 L228 K Q K S R R K L K R G K K E V
Rat Rattus norvegicus Q924S5 950 105774 L229 K Q K S R R K L K R G K K E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506549 791 89382 V141 L M V E V E N V S H E D F Q V
Chicken Gallus gallus XP_001232112 790 89040 P140 K K E A E E E P G A K E Q A V
Frog Xenopus laevis Q2TAF8 856 94553 P184 N L P K E L L P D V L T S I I
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 V186 P K E T L P D V L A A M I R T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649133 1006 112875 T231 G R I P R S R T G K S R E S A
Honey Bee Apis mellifera XP_392970 995 112847 T260 N I S E N K I T E G I Q E K V
Nematode Worm Caenorhab. elegans O44952 971 108188 T195 E I T P K N E T P L N G R R A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P93648 964 105641 K210 T V K V D H L K E K P Y N K D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93655 940 103912 S186 G T L A Q I S S I Q G D Q V I
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 V345 E L Q H H K R V E A T E E E S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.6 93.7 N.A. 87.4 88.6 N.A. 71.6 73.8 32.2 32.7 N.A. 59.4 58.9 51.5 N.A.
Protein Similarity: 100 99.6 89 96 N.A. 92 92.8 N.A. 77 78.5 50.8 52.3 N.A. 73.3 74.9 67.2 N.A.
P-Site Identity: 100 100 100 80 N.A. 73.3 73.3 N.A. 0 6.6 0 0 N.A. 20 0 13.3 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 73.3 73.3 N.A. 6.6 33.3 0 6.6 N.A. 53.3 40 46.6 N.A.
Percent
Protein Identity: N.A. 48.7 N.A. 48.1 39.1 N.A.
Protein Similarity: N.A. 65.8 N.A. 65.4 57.1 N.A.
P-Site Identity: N.A. 6.6 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 26.6 N.A. 33.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 0 0 0 0 19 7 0 0 7 32 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 7 0 7 0 0 13 0 0 7 % D
% Glu: 13 0 13 13 13 13 13 0 19 0 7 13 19 44 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 13 0 0 0 0 0 0 0 13 7 44 7 0 0 0 % G
% His: 0 19 0 7 7 7 0 0 0 7 0 0 0 0 0 % H
% Ile: 0 13 7 0 0 7 7 0 7 0 7 0 7 7 13 % I
% Lys: 44 13 44 7 7 13 38 7 38 13 7 38 38 13 0 % K
% Leu: 7 13 7 0 7 7 13 13 7 7 7 0 0 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 13 0 0 0 7 7 7 0 0 0 7 0 7 0 0 % N
% Pro: 7 0 7 38 0 7 0 13 7 0 7 0 0 0 0 % P
% Gln: 0 19 7 0 7 0 0 0 0 7 0 7 13 7 0 % Q
% Arg: 0 7 0 0 44 38 13 0 0 38 0 7 7 13 0 % R
% Ser: 0 0 7 13 0 7 7 25 7 0 7 0 7 7 7 % S
% Thr: 7 7 7 7 0 0 0 25 0 0 7 7 0 0 7 % T
% Val: 0 7 7 7 7 0 0 19 0 7 0 0 0 7 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _